N-Isovaleroylglycine-d 2

Overview

N-Isovaleroylglycine -d 2 is the deuterium labeled N-Isovaleroylglycine ( HY-W015464 ). N-Isovaleroylglycine is a peptidylglycine α-amidating monooxygenase ( PAM ) inhibitor with a K i value of 2.0 mM against human hsPAM . N-Isovaleroylglycine undergoes oxidative cleavage by purified rat PAM to produce fatty acid amide and glyoxylic acid. N-Isovaleroylglycine exerts competitive inhibition by binding to hsPAM, blocking the amidation of dansyl-Tyr-Val-Gly. N-Isovaleroylglycine exhibits lowered urinary abundance in MRSA-infected mice, which qualifies it as a non-invasive biomarker. N-Isovaleroylglycine can be used in studies related to Staphylococcus aureus pneumonia and diabetic foot.

Application

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Product Information

• Catalog No.: HY-W015464S1
• CAS No.: 1219795-09-1
• Molecular Formula: C7H11D2NO3
• Molecular Weight: 161.20
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source