trans-Aconitic acid

Overview

trans-Aconitic acid is an orally active aconitase inhibitor that non-competitively inhibits the conversion of citric acid to cis-aconitic acid and competitively inhibits the conversion of cis-aconitic acid to isocitric acid. trans-Aconitic acid inhibits the growth of Leishmania donovani promastigotes, the transformation of Leishmania donovani amastigotes to promastigotes, and the in vitro proliferation of Leishmania donovani amastigotes within macrophages in vitro. trans-Aconitic acid can be used in research related to visceral leishmaniasis (kala-azar).

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Parasitic Infection | Products > Disease Areas > Leishmania Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Parasite

Product Information

• Catalog No.: HY-W016813
• CAS No.: 4023-65-8
• Molecular Formula: C6H6O6
• Molecular Weight: 174.11
• Purity: 99.74%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 50 mg/mL (287.17 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source