RHC 80267

Overview

RHC 80267 (U-57908) is a potent and selective inhibitor of diacylglycerol lipase ( DAGL ) (with IC 50 of 4 μM in canine platelets). RHC-80267 inhibits cholinesterase activity with an IC 50 of 4 μM, thereby enhancing the relaxation evoked by acetylcholine . RHC 80267 also inhibits COX and the hydrolysis of phosphatidylcholine (PC) .

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Neurological Disease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Phospholipase | Products > Signaling Pathways > DAGL | Products > Signaling Pathways > Acyltransferase | Products > Signaling Pathways > mAChR | Products > Signaling Pathways > COX

Product Information

• Catalog No.: HY-107416
• CAS No.: 83654-05-1
• Molecular Formula: C20H34N4O4
• Molecular Weight: 394.51
• Purity: 99.41%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (6.34 mM); Clear solution
• Availability: In-stock

Source

Original product source