AY 9944 (Standard)

Overview

AY 9944 (Standard) is the analytical standard of AY 9944 ( HY-107420 ). This product is intended for research and analytical applications. AY 9944 is a specific cholesterol biosynthesis inhibitor. AY 9944 inhibits the 7-dehydro cholesterol Δ7-reductase (DHCR7) enzyme with an IC 50 of 13 nM. AY 9944 causes hypocholesterolemia and accumulation of 7DHC. At high doses, AY 9944 inhibits also in cultured embryos sterol Δ7-Δ8 isomerase, which causes the accumulation of cholest-8-en-3β-ol.

Application

Products | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Others | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Endogenous Metabolite | Products > Signaling Pathways > Reference Standards

Product Information

• Catalog No.: HY-107420R
• CAS No.: 366-93-8
• Molecular Formula: C22H30Cl4N2
• Molecular Weight: 464.30
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source