Carveol

Overview

Carveol is an orally active monoterpenoid alcohol with neuroprotective, antioxidant, anti-inflammatory, anticonvulsant, antidiabetic, hypolipidemic and hepatoprotective activities. Carveol upregulates the expression of Bcl2 , downregulates the expression of caspase-3 , TNF-α , IL1β and IL6 , activates the Nrf2 / HO-1 antioxidant signaling pathway, inhibits the RAGE / NF-κB signaling pathway, and suppresses neuroinflammation and neuronal apoptosis . Carveol inhibits α-synuclein aggregation, improves cognitive ability, and inhibits α-amylase activity. Carveol exerts neuroprotective effects in a rat model of Parkinson's disease. Carveol exhibits antidiabetic effects in alloxan-induced diabetic rats. Carveol alleviates PTZ-induced seizures in rats. Carveol can be used in research related to Parkinson's disease, epilepsy, diabetes and ischemic stroke.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Oxidative Stress and Inflammation | Products > Disease Areas > Epilepsy | Products > Disease Areas > Glucose Metabolism | Products > Disease Areas > Parkinson's Disease | Products > Disease Areas > Antioxidant Agent | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Research Areas > Metabolic Disease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Interleukin Related | Products > Signaling Pathways > Keap1-Nrf2 | Products > Signaling Pathways > Heme Oxygenase (HO) | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > α-synuclein | Products > Signaling Pathways > Amylases | Products > Signaling Pathways > Bcl-2 Family | Products > Signaling Pathways > Caspase | Products > Signaling Pathways > TNF Receptor

Product Information

• Catalog No.: HY-W017370
• CAS No.: 99-48-9
• Molecular Formula: C10H16O
• Molecular Weight: 152.24
• Purity: 98.32%
• Storage: -20°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Solubility: ≥ 2.5 mg/mL (16.42 mM); Clear solution
• Availability: In-stock

Source

Original product source