DHICA

DHICA
  • CAS No.:4790-08-3
  • Grade:96.26%
  • Formula:C9H7NO4
  • M.W.:193.16
  • Solvent:≥ 2.5 mg/mL (12.94 mM); Clear solution

Overview

DHICA (5,6-Dihydroxyindole-2-carboxylic acid) is an eumelanin building block, GPR35 agonist and melanin synthesis intermediate. DHICA activates GPR35 , triggering dynamic mass redistribution and β-arrestin translocation. DHICA interacts with DNA and interferes with Fpg activity . DHICA promotes the generation of single-strand breaks in plasmid DNA. DHICA increases the activity and expression levels of SOD and Catalase . DHICA is applicable to research related to skin cancer and colon cancer .

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Colorectal Cancer | Products > Disease Areas > Digestive System Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Others | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > DNA/RNA Synthesis | Products > Signaling Pathways > Drug Intermediate | Products > Signaling Pathways > SOD | Products > Signaling Pathways > Endogenous Metabolite | Products > Signaling Pathways > GPR35 | Products > Signaling Pathways > Arrestin

Product Information

  • Catalog No.: HY-W018158
  • CAS No.: 4790-08-3
  • Molecular Formula: C9H7NO4
  • Molecular Weight: 193.16
  • Purity: 96.26%
  • Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
  • Solubility: ≥ 2.5 mg/mL (12.94 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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