Hexadecanedioic acid

Overview

Hexadecanedioic acid (Thapsic acid) is an orally active metabolite produced by B. uniformis . Hexadecanedioic acid inhibits IRE1α-XBP1s -mediated flipogenesis and ferroptosis . Hexadecanedioic acid downregulates XBP1 and Hrd1 expression, activates the Nrf2/SLC7A11/GPX4 pathway. Hexadecanedioic acid can be used for the research of metabolic-associated fatty liver disease.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > IRE1 | Products > Signaling Pathways > Ferroptosis | Products > Signaling Pathways > Keap1-Nrf2 | Products > Signaling Pathways > Glutathione Peroxidase

Product Information

• Catalog No.: HY-W018161
• CAS No.: 505-54-4
• Molecular Formula: C16H30O4
• Molecular Weight: 286.41
• Purity: 98.0%
• Storage: Store at room temperature 3 years. In solvent -80°C, 2 years , -20°C, 1 year
• Availability: In-stock

Source

Original product source