Bifendate

Overview

Bifendate (DDB), extracted from Schisandrae chinensis , is an orally active anti-HBV agent against chronic hepatitis B. Bifendate inhibits ATG5-dependent autophagy and attenuates oleic acid-induced lipid accumulation with anti-oxidant properties in vitro. Bifendate can decrease alanine transaminase (ALT) level in mice. Bifendate attenuates hepatic steatosis in cholesterol/bile salt- and high-fat diet-induced hypercholesterolemia in mice. Bifendate potently increases the activity of cytochrome proteins ( CYPs ) and reverse P-gp -mediated multi-drug resistance (MDR).

Application

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Product Information

• Catalog No.: HY-W018791
• CAS No.: 73536-69-3
• Molecular Formula: C20H18O10
• Molecular Weight: 418.35
• Purity: 99.92%
• Storage: 4°C, protect from light, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
• Solubility: ≥ 1.25 mg/mL (2.99 mM); Clear solution
• Availability: In-stock

Source

Original product source