7-Chloro-4-(piperazin-1-yl)quinoline

Overview

7-Chloro-4-(piperazin-1-yl) quinolone is an important scaffold in medicinal chemistry. 7-Chloro-4-(piperazin-1-yl) quinolone is a potent sirtuin inhibitor and also inhibits the serotonin uptake ( IC 50 of 50 μM). 7-Chloro-4-(piperazin-1-yl) quinolone exhibits antimalarial activity on D10 and K1 strains of P. falciparum with IC 50 s of 1.18 μM and 0.97 μM, respectively.

Application

Products | Products > Disease Areas > Parasitic Infection | Products > Disease Areas > Digestive System Inflammation | Products > Disease Areas > Infection | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Digestive System Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Sirtuin | Products > Signaling Pathways > Parasite

Product Information

• Catalog No.: HY-W020111
• CAS No.: 837-52-5
• Molecular Formula: C13H14ClN3
• Molecular Weight: 247.72
• Purity: 98.63%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 1.67 mg/mL (6.74 mM); Clear solution
• Availability: In-stock

Source

Original product source