TFB-TBOA

Overview

TFB-TBOA (CF3-Bza-TBOA) is a potent glutamate transporter blocker that potently suppresses the activity of glial transporters. TFB-TBOA shows IC 50 values of 22, 17, and 300 nM for glutamate transporters EAAT1 , EAAT2 , and EAAT3 respectively in an uptake assay using cells transiently expressing EAATs.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > EAAT

Product Information

• Catalog No.: HY-107521
• CAS No.: 480439-73-4
• Molecular Formula: C19H17F3N2O6
• Molecular Weight: 426.34
• Purity: 99.96%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 1.25 mg/mL (2.93 mM); Clear solution
• Availability: In-stock

Source

Original product source