Gap 26

Overview

Gap 26 is a gap junction blocker which is corresponding to residues 63 - 75 of connexin 43. Gap 26 was shown to attenuate rhythmic contractile activity of rabbit arterial smooth muscle (IC50 = 28.4 μM). It also inhibits IP3-induced ATP release but does not inhibit gap junctional coupling in endothelial cells. Sequence: VCYDKSFPISHVR Source summary: Gap 26 is a peptide inhibitor used in cardiovascular and cancer research, targeting gap junctions to regulate cellular communication.

Application

Products > Drug Discovery > Inhibitor > Other Inhibitors | Products > Drug Discovery > Inhibitor

Product Information

• Catalog No.: B2693-077119
• CAS No.: 197250-15-0
• Molecular Formula: C70H107N19O19S
• Molecular Weight: 1550.78
• Purity: 98%
• Storage: Store at -20°C
• Solubility: Soluble in Water

Source

Original product source