3-Hydroxy-2-pyrone (Compound 12d) is a metalloenzyme inhibitor. 3-Hydroxy-2-pyrone shows an inhibition rate of approximately 50% for matrix metalloproteinases ( MMP ) and the inhibition rate for non-heme iron enzyme 5-lipoxygenase ( 5-LOX ) was over 70% at 1 mM. 3-Hydroxy-2-pyrone also has certain inhibitory activity against copper-dependent enzyme tyrosinase . 3-Hydroxy-2-pyrone can be used for the research of cancer , infection and inflammation.
Products | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Infection | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > MMP | Products > Signaling Pathways > Lipoxygenase | Products > Signaling Pathways > Tyrosinase
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