CYP2E1-IN-1

Overview

CYP2E1-IN-1 (Compound 10) is an orally active cytochrome P450 2E1 ( CYP2E1 ) inhibitor with a K d of 7.02 μM, an IC 50 of 1.64 μM, and a K i of 0.897 μM. CYP2E1-IN-1 activates the Nrf2/HO-1 signaling pathway and inhibits ROS production, thereby alleviating pancreatic injury. CYP2E1-IN-1 has significant anti-inflammatory and antioxidant activities and can effectively reduce inflammation and oxidative stress in severe acute pancreatitis (SAP). CYP2E1-IN-1 can be used in the study of SAP and other inflammatory-related diseases.

Application

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Product Information

• Catalog No.: HY-W072025
• CAS No.: 38205-55-9
• Molecular Formula: C6H7NOS
• Molecular Weight: 141.19
• Purity: 99.76%
• Storage: Store at room temperature 3 years. In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 5 mg/mL (35.41 mM); Clear solution
• Availability: In-stock

Source

Original product source