ATC0065 free base is a potent, selective and orally active melanin-concentrating hormone (MCH) receptor 1 ( MCHR1 ) antagonist with an IC 50 of 15.7 nM for human MCHR1 . ATC0065 free base does not exhibits significant activity for MCHR2. ATC0065 free base has anxiolytic and antidepressant activities.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > MCHR1 (GPR24) | Products > Signaling Pathways > 5-HT Receptor
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