Alloc-Val-Ala-OH

Overview

Alloc-Val-Ala-OH (((Allyloxy)carbonyl)-L-valyl-L-alanine) is a building block in the synthesis of Tesirine, a clinical antibody-drug conjugate (ADC) pyrrolobenzodiazepine (PBD) dimer payload. The Val-Ala will specifically be cleaved by Cathepsin B . The Alloc group is stable to treatment with piperidine and TFA, but can be easily removed under mild conditions by palladium catalyzed allyl transfer.

Application

Products | Products > Signaling Pathways > Others | Products > Research Areas > Others | Products > Signaling Pathways > Biochemical Assay Reagents

Product Information

• Catalog No.: HY-W076556
• CAS No.: 330970-70-2
• Molecular Formula: C12H20N2O5
• Molecular Weight: 272.30
• Purity: 99.98%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source