Arundic Acid

Overview

Arundic Acid is an orally effective astrocyte function modulator and neuroprotective agent. Arundic Acid increases the expression and function of the astrocytic glutamate transporter EAAT1 by activating the ERK , Akt and NF-κB pathways. Arundic Acid attenuates retinal ganglion cell death in a normal-tension glaucoma model. Arundic Acid exerts neuroprotective effects in a mouse model of Parkinson's disease. Arundic Acid is a S100β protein synthesis inhibitor that prevents neurological deficits and brain tissue damage after intracerebral hemorrhage in rats. Arundic Acid downregulates neuroinflammation and astrocytic dysfunction after status epilepticus in immature rats. Arundic Acid is applicable to research related to Parkinson's disease, cerebral ischemia, glaucoma, intracerebral hemorrhage and epilepsy.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Visual System Disease | Products > Disease Areas > Cerebrovascular Disease | Products > Disease Areas > Epilepsy | Products > Disease Areas > Parkinson's Disease | Products > Disease Areas > Glaucoma | Products > Disease Areas > Brain Hemorrhage | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > EAAT | Products > Signaling Pathways > ERK | Products > Signaling Pathways > Akt | Products > Signaling Pathways > NF-κB

Product Information

• Catalog No.: HY-107661
• CAS No.: 185517-21-9
• Molecular Formula: C11H22O2
• Molecular Weight: 186.29
• Purity: 98.0%
• Storage: Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 3.75 mg/mL (20.13 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source