L-p-Boronophenylalanine

Overview

L-p-Boronophenylalanine is a boron-containing substrate for L-type amino acid transporters ( L AT 1 and L AT 2 ). L-p-Boronophenylalanine enters tumor cells by competing with natural amino acids for LAT, selectively accumulating boron in cancer cells. L-p-Boronophenylalanine can be used in boron neutron capture therapy (BNCT) . When boron-10 captures thermal neutrons, a nuclear reaction occurs, producing high-energy alpha particles and lithium nuclei, which kill cancer cells at close range with little damage to surrounding tissues. L-p-Boronophenylalanine can be used in cancer research, especially glioblastoma and anaplastic astrocytoma.

Application

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Product Information

• Catalog No.: HY-W087830
• CAS No.: 76410-58-7
• Molecular Formula: C9H12BNO4
• Molecular Weight: 209.01
• Purity: 99.79%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source