trans-2-Nonenal

Overview

trans-2-Nonenal (trans-2-Nonen-1-al) is an endogenous peroxidation product of polyunsaturated fatty acids, acting as an inhibitor of COX and 12-LOX , as well as an inducer of apoptosis . trans-2-Nonenal is also a malodorous compound secreted by the human body, and its content gradually increases with aging. trans-2-Nonenal inhibits the activities of multiple enzymes such as platelet membrane-bound PTPase , preferentially covalently modifies proteins at lysine residues to form immunogenic adducts, and regulates platelet Arachidonic acid ( HY-109590 ) metabolism. trans-2-Nonenal also exhibits significant cytotoxicity, reduces the viability of keratinocytes, promotes their apoptosis , and effectively decreases the thickness of epidermal models and the number of proliferating cells. trans-2-Nonenal is commonly used in studies of thrombotic, atherosclerotic diseases, renal adenocarcinoma, etc..

Application

Products | Products > Disease Areas > Chronic Disease and Inflammation | Products > Disease Areas > Cardiovascular Disease | Products > Disease Areas > Atherosclerosis and Inflammation | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > COX | Products > Signaling Pathways > Lipoxygenase | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-W089800
• CAS No.: 18829-56-6
• Molecular Formula: C9H16O
• Molecular Weight: 140.22
• Purity: 98.99%
• Storage: 4°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Solubility: ≥ 5 mg/mL (35.66 mM); Clear solution
• Availability: In-stock

Source

Original product source