4-Chloropyridine is a NNMT (Nicotinamide N-methyltransferase) substrate and suicide inhibition-based protein labeling scaffold precursor.4-Chloropyridine undergoes NNMT -catalyzed pyridine nitrogen methylation to increase C4 electrophilicity, enabling aromatic nucleophilic substitution by NNMT cysteine C159 for covalent NNMT modification and inactivation.4-Chloropyridine can be used for the research of various cancers.
Products | Products > Disease Areas > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Others | Products > Signaling Pathways > Amine N-methyltransferase
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