(±)-J-113397

Overview

(±)-J-113397 is a potent and selective non-peptidyl ORL1 receptor antagonist with a K i of 1.8 nM for cloned human ORL1. J-113397 inhibited nociceptin/orphanin FQ-stimulated GTPγS binding to CHO cells expressing ORL1 with an IC 50 value of 5.3 nM. J-113397 can be used for researching the physiological roles of nociceptin/orphanin FQ.

Application

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Product Information

• Catalog No.: HY-107721
• CAS No.: 217461-40-0
• Molecular Formula: C24H37N3O2
• Molecular Weight: 399.57
• Purity: 99.82%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Solubility: ≥ 2.5 mg/mL (6.26 mM); Clear solution
• Availability: In-stock

Source

Original product source