Geranial is an aromatic compound. It can be isolated from the fruits of Litsea cubeba Lour and the rhizomes of ginger ( Zingiber officinale ). Geranial inhibits LPS-induced phosphorylation of ERK1/2 , JNK1/3 and IκB in macrophages. It suppresses the secretion of IL-1β , TNF-α and IL-6 , as well as the expression of pro-IL-1β , iNOS and COX-2 . Geranial increases ROS . It can be used in the research of inflammatory diseases.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > ERK | Products > Signaling Pathways > JNK | Products > Signaling Pathways > IKK | Products > Signaling Pathways > COX | Products > Signaling Pathways > NO Synthase | Products > Signaling Pathways > Reactive Oxygen Species (ROS) | Products > Signaling Pathways > TNF Receptor | Products > Signaling Pathways > Interleukin Related
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