Croconic acid disodium

Overview

Croconic acid disodium (Nacr) is a lysine crotonylation ( Kcr ) activator and electroactive material. Croconic acid disodium reduces the expression of HDAC2 , HDAC3 , SIRT1 , and SIRT3 , and increases the expression of EP300 , CITED1 , ACSS2 , DPF2 , CDYL , MLLT3 , and YEATS2 . Croconic acid disodium elevates intracellular crotonyl-CoA content and global histone lysine crotonylation levels. Croconic acid disodium promotes the growth of bovine fibroblasts, regulates cell cycle progression, and inhibits bovine fibroblast apoptosis ( apoptosis ). Croconic acid disodium improves the blastocyst development efficiency of bovine somatic cell nuclear transfer embryos. Croconic acid disodium undergoes reversible lithium intercalation/deintercalation reactions via sodium-lithium ion exchange. Croconic acid disodium is applicable to research related to cell growth promotion.

Application

Products | Products > Disease Areas > Others | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Others | Products > Signaling Pathways > HDAC | Products > Signaling Pathways > Sirtuin | Products > Signaling Pathways > CDK | Products > Signaling Pathways > Bcl-2 Family | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-W105310A
• CAS No.: 14379-00-1
• Molecular Formula: C5Na2O5
• Molecular Weight: 186.03
• Purity: 99.98%
• Storage: Store at room temperature, keep dry and cool. In solvent -80°C, 1 year , -20°C, 6 months
• Availability: In-stock

Source

Original product source