DTME

Overview

DTME (dithio-bis-maleimidoethane) is a homobifunctional, maleimide crosslinker specifically designed for conjugation between sulfhydryl groups (-SH). DTME, whose molecular structure consists of two maleimide groups connected by an ethylene disulfide bridge, can specifically react with thiol - containing molecules (such as cysteine residues) to form stable covalent bonds. DTME allows crosslinks that can be cleaved with reducing agents such as DTT ( HY-15917 ). DTME is commonly utilized to explore and characterize protein structure, particularly oligomerization, or protein interactions.

Application

Products | Products > Signaling Pathways > Others | Products > Research Areas > Others | Products > Signaling Pathways > Biochemical Assay Reagents

Product Information

• Catalog No.: HY-W106411
• CAS No.: 71865-37-7
• Molecular Formula: C12H12N2O4S2
• Molecular Weight: 312.36
• Purity: 99.03%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (8.00 mM); Clear solution
• Availability: In-stock

Source

Original product source