Topoisomerase IIα-IN-9 (NSC85582) is a bisphenol compound that has a moderate inhibitory effect on DNA topoisomerase Topoisomerase II ( IC 50 : 571 μM). Topoisomerase II α-IN-9 also exhibits a certain cell growth inhibitory effect, with IC 50 s of 117 μM and 218 μM for K562 and CHO, respectively.
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