Talotrexin monoammonium

Overview

Talotrexin monoammonium is the monoammonium salt form of Talotrexin ( HY-10824 ). Talotrexin monoammonium is an analog of Aminopterin ( HY-14518 ), and is a nonpolyglutamatable classic antifolate . Talotrexin monoammonium is a reduced folate carrier (RFC) specific inhibitor and selectively inhibits RFC transport. Talotrexin monoammonium shows antitumor activity by targeting DHFR to inhibit tumor growth.

Application

Products | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Dihydrofolate reductase (DHFR) | Products > Signaling Pathways > Antifolate

Product Information

• Catalog No.: HY-10824A
• CAS No.: 648420-92-2
• Molecular Formula: C27H30N10O6
• Molecular Weight: 590.59
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source