(S)-3-Hydroxy Midostaurin

Overview

(S)-3-Hydroxy Midostaurin ((S)-CGP52421) is a potent kinases inhibitor with IC 50 values of <400 nM for 13 kinases (VEGFR-2, TRK-A, FLT3 , et). (S)-3-Hydroxy Midostaurin is a minor metabolite of midostaurin (PKC412; HY-10230) undergoing by the hepatic CYP3A4 enzyme. (S)-3-Hydroxy Midostaurin has the potential for acute myeloid leukemia (AML).

Application

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Product Information

• Catalog No.: HY-108263A
• CAS No.: 945260-14-0
• Molecular Formula: C35H30N4O5
• Molecular Weight: 586.64
• Purity: 96.07%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source