WRX606

Overview

WRX606 is an orally active nonrapalog inhibitor for mTOR complex 1 ( mTORC1M ). WRX606 inhibits the phosphorylation of mTORC1 substrate S6 kinase 1 ( S6K1 ) ( IC 50 = 10 nM) and eukaryotic translation initiation factor 4E binding protein (p-4E-BP1) ( IC 50 = 0.27 μM) in MCF-7 cells. WRX606 suppresses tumor growth in mice without promotion of metastasis. WRX606 can be studied in research as an antitumor agent.

Application

Products | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > mTOR

Product Information

• Catalog No.: HY-W348485
• CAS No.: 899937-47-4
• Molecular Formula: C28H25ClN4O6
• Molecular Weight: 548.97
• Purity: 95.65%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source