PT-ttpy

Overview

Pt-ttpy, a metallo-organic complex and potent G-quadruplex ligand, effectively triggers substantial telomere-related DNA damage in cancer cells by inhibiting telomerase and/or telomere functions, while also causing various chromatin abnormalities during mitosis , such as chromatin bridges, ultrafine bridges (UFBs), and double-stranded breaks (DSBs).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > G-quadruplex | Products > Signaling Pathways > Mitosis | Products > Signaling Pathways > DNA/RNA Synthesis

Product Information

• Catalog No.: HY-W543137
• CAS No.: 727721-37-1
• Molecular Formula: C22H17Cl2N3Pt
• Molecular Weight: 589.38
• Purity: 98.0%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source