Onalespib

Overview

Onalespib, also known as AT13387, is a synthetic, orally bioavailable, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. AT13387 selectively binds to Hsp90, thereby inhibiting its chaperone function and promoting the degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Cancer | HSP

Product Information

• Catalog No.: B2693-456213
• CAS No.: 912999-49-6
• Molecular Formula: C24H31N3O3
• Molecular Weight: 409.52
• Purity: >98%
• Storage: 3 years -20°C powder, 6 months -80°C in solvent.
• Solubility: DMSO:≥ 40 mg/mL

Source

Original product source