GSTO1-IN-3

Overview

GSTO1-IN-3 is a potent GSTO1-1 inhibitor with an IC 50 of 0.11 μM, and shows selectivity over GSTO2-2, GSTA1-1 and GSTP1-1 ( IC 50 > 100 μM). GSTO1-IN-3 enhances the cytotoxicity of Cisplatin ( HY-17394 ) against human breast cancer cells. GSTO1-IN-3 inhibits IL-1β release in mouse bone marrow-derived macrophage (BMDM) cells. GSTO1-IN-3 attenuates inflammation in mice. GSTO1-IN-3 can be used for breast cancer and inflammation research.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Breast Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Glutathione S-transferase | Products > Signaling Pathways > Interleukin Related

Product Information

• Catalog No.: HY-W615446
• CAS No.: 158890-32-5
• Molecular Formula: C14H18ClNO
• Molecular Weight: 251.75
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source