GeA-69

Overview

GeA-69 is a selective, allosteric inhibitor of poly-adenosine-diphosphate-ribose polymerase 14 ( PARP14 ) targeting macrodomain 2 ( MD2 ), with a K d value of 2.1 μM. GeA-69 involves in DNA damage repair mechanisms and prevents recruitment of PARP14 MD2 to sites of laser-induced DNA damage.

Application

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Product Information

• Catalog No.: HY-108708
• CAS No.: 2143475-98-1
• Molecular Formula: C20H16N2O
• Molecular Weight: 300.35
• Purity: 99.91%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.08 mg/mL (6.93 mM); Clear solution
• Availability: In-stock

Source

Original product source