Cannflavin A

Overview

Cannflavin A can be isolated from Cannabis sativa L. . Cannflavin A has anti-cancer, neuroprotective and anti-inflammatory activity. Cannflavin A inhibits Aβ 1-42 aggregation. Cannflavin A also inhibits kynurenine-3-monooxygenase ( KMO ) ( IC 50 = 29.4 μM). Cannflavin A activates apoptosis via caspase-3 cleavage . Cannflavin A exerts anti-inflammatory effects by inhibiting pro-inflammatory enzymes , including prostaglandin E2 and cytochrome c oxidases I and II in PC12 cell line.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Amyloid-β | Products > Signaling Pathways > KMO

Product Information

• Catalog No.: HY-W748591
• CAS No.: 76735-57-4
• Molecular Formula: C26H28O6
• Molecular Weight: 436.50
• Purity: 99.20%
• Storage: -20°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source