JK-P3

Overview

JK-P3 is a potent and pan VEGFR2 inhibitor, with IC 50 s of 7.83 μM, 27 μM and 5.18 μM for VEGFR2, FGFR1 and FGFR3, respectively. JK-P3 can inhibit VEGF-A-stimulated VEGFR2 activation and intracellular signalling, also inhibits endothelial monolayer wound closure and angiogenesis, as well as fibroblast growth factor receptor kinase activity in vitro . JK-P3 has anti-angiogenic activity.

Application

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Product Information

• Catalog No.: HY-108933
• CAS No.: 942655-44-9
• Molecular Formula: C18H17N3O3
• Molecular Weight: 323.35
• Purity: 99.75%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.5 mg/mL (7.73 mM); Clear solution
• Availability: In-stock

Source

Original product source