Doravirine

Overview

Doravirine is a non-nucleoside reverse transcriptase inhibitor under development of Merck & Co. IC 50 value is 12 nM against the wild type, 21nM against K103N, 31 nM against Y181C, 33nM against K103N/Y181C mutant viruses in vitro. MK-1439 exhibited similar antiviral activities against 10 different HIV-1 subtype viruses. Phase III for the treatment of HIV-1 infections is on-going.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Cancer | DNA/RNA Synthesis

Product Information

• Catalog No.: B2693-475314
• CAS No.: 1338225-97-0
• Molecular Formula: C17H11ClF3N5O3
• Molecular Weight: 425.75
• Purity: 98%
• Storage: -20°C Freezer
• Solubility: Soluble in DMSO

Source

Original product source