Neral

Overview

Neral is a plant-derived anti-inflammatory, antioxidant and anticancer agent. Neral inhibits the phosphorylation of ERK1/2 , p38 MAPK and IκB in macrophages induced by LPS ( HY-D1056 ), suppresses the secretion of TNF-α and IL-6 , as well as the expression of pro-IL-1β , iNOS and COX-2 in cells, and reduces the production of ROS in cells. Neral inhibits the activation of the NLRP3 inflammasome, and decreases the activation of caspase-1 and the secretion of IL-1β in mouse macrophages. Neral induces autophagy , and exhibits antiproliferative activity both in in vitro breast cancer cell models and mouse xenograft models. Neral regulates brassinosteroid, jasmonic acid and ethylene signaling pathways, and induces the expression of AP2/ERF-ERF and bHLH family genes in rice roots. Neral acts as a herbicide safener, alleviates the damage induced by Fenoxaprop-P-ethyl ( HY-B2013 ), and promotes the elongation of rice roots. Neral can be used in research related to breast cancer , inflammatory and immune system diseases, and herbicide safeners.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Breast Cancer | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Autophagy | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > COX | Products > Signaling Pathways > TNF Receptor | Products > Signaling Pathways > NOD-like Receptor (NLR) | Products > Signaling Pathways > NO Synthase | Products > Signaling Pathways > PERK | Products > Signaling Pathways > p38 MAPK | Products > Signaling Pathways > Reactive Oxygen Species (ROS) | Products > Signaling Pathways > Caspase | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Herbicide | Products > Signaling Pathways > Interleukin Related

Product Information

• Catalog No.: HY-W923189
• CAS No.: 106-26-3
• Molecular Formula: C10H16O
• Molecular Weight: 152.23
• Purity: 97.87%
• Storage: -20°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Availability: In-stock

Source

Original product source