Temozolomide Acid

Overview

Temozolomide acid is an active metabolite of temozolomide(T017775) with anticancer activity in vitro. Temozolomide is an alkylating agent used as a treatment of some brain cancer, a second-line treatment for astrocytoma and a first-line treatment for glioblastoma multiforme.In Apr 2016, Stanford University and Merck suspended enrolment in a phase II trial for Acute myeloid leukaemia (Combination therapy, Newly diagnosed, Second-line therapy or greater) in USA. In 14 Jul 2016, Medivation planed a phase II trial for Endometrial cancer in USA (NCT02836028) After two days, M.D. Anderson Cancer Center completed a phase II trial in Malignant melanoma (Late-stage disease, Neoadjuvant therapy, Monotherapy, Combination therapy) in USA .

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Cancer | DNA/RNA Synthesis

Product Information

• Catalog No.: B2694-161090
• CAS No.: 113942-30-6
• Molecular Formula: C6H5N5O3
• Molecular Weight: 195.14
• Purity: 98%
• Storage: -20°C Freezer
• Solubility: DMSO, Methanol

Source

Original product source