2,6-Dihydroxyacetophenone

Overview

2,6-Dihydroxyacetophenone, a polyphenolic derivative of Acetophenone ( HY-Y0989 ), is an orally active mTOR inhibitor. 2,6-Dihydroxyacetophenone shows antioxidant activity. 2,6-Dihydroxyacetophenone inhibits cell growth and proliferation in CRC cells. 2,6-Dihydroxyacetophenone arrests at G0/G1 phase of cell cycle, induces apoptosis and suppresses cell migration in CRC cells. 2,6-Dihydroxyacetophenone inhibits xanthine oxidase ( XOD ) with an IC 50 of 1.24 mM. 2,6-dihydroxyacetophenone improves uric acid metabolism in hyperuricemia mice, reduces plasma cholesterol in hypercholesterolemic rats, and inhibits lipid accumulation in HFD-induced obese mice. 2,6-Dihydroxyacetophenone can be used for the study of colorectal cancer (CRC), hyperuricemia and hypercholesterolemia.

Application

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Product Information

• Catalog No.: HY-Y0106
• CAS No.: 699-83-2
• Molecular Formula: C8H8O3
• Molecular Weight: 152.15
• Purity: 99.85%
• Storage: 4°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Solubility: ≥ 2.5 mg/mL (16.43 mM); Clear solution
• Availability: In-stock

Source

Original product source