RO-28-2653

Overview

RO-28-2653 is an orally active matrix metalloproteinase ( MMP ) inhibitor. RO-28-2653 exhibits highly selective inhibitory effects on MMP2 , MMP9 and membrane-type 1-MMP , and may reduce side effects (such as musculoskeletal pain) compared to broad-spectrum MMP inhibitors. RO-28-2653 shows significant tumor growth inhibition in a rat prostate model. RO-28-2653 can be used in studies of hormone-sensitive tumors.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > MMP

Product Information

• Catalog No.: HY-109747
• CAS No.: 261956-22-3
• Molecular Formula: C26H23N5O5
• Molecular Weight: 485.49
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source