Tivozanib

Tivozanib
  • CAS No.:475108-18-0
  • Grade:99.80%
  • Formula:C22H19ClN4O5
  • M.W.:454.86
  • Solvent:≥ 2.5 mg/mL (5.50 mM); Clear solution

Overview

Tivozanib (AV-951; KRN951) is a selective, orally active inhibitor for vascular endothelial growth factor receptor ( VEGFR )-1, 2 3, with IC 50 s of 30, 6.5 and 15 nM, respectively. Tivozanib exhibits antitumor efficacy.

Application

Products | Products > Disease Areas > Lipid Metabolism | Products > Disease Areas > Pulmonary Disease | Products > Disease Areas > Lung Cancer | Products > Disease Areas > Breast Cancer | Products > Disease Areas > Colorectal Cancer | Products > Disease Areas > Digestive System Cancer | Products > Disease Areas > Prostate Cancer | Products > Disease Areas > Urogenital Cancer | Products > Disease Areas > Gastric Cancer | Products > Disease Areas > Liver Cancer | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Disease Areas > Blood Disease | Products > Disease Areas > Pancreatic Cancer | Products > Disease Areas > Ovarian Cancer | Products > Disease Areas > Obesity | Products > Disease Areas > Lung Fibrosis | Products > Disease Areas > Cancer | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Urogenital Disease | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > VEGFR

Product Information

  • Catalog No.: HY-10977
  • CAS No.: 475108-18-0
  • Molecular Formula: C22H19ClN4O5
  • Molecular Weight: 454.86
  • Purity: 99.80%
  • Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
  • Solubility: ≥ 2.5 mg/mL (5.50 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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