SHP099

Overview

SHP099 is a potent, selective, orally bioavailable, and efficacious SHP2 inhibitor (IC50 value 0.071 μM) that stabilizes SHP2 in an auto-inhibited conformation. SHP099 suppresses signaling through the Ras-ERK pathway and blocks the proliferation of receptor tyrosine kinase-driven human cancer cells in vitro and in vivo.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Cancer | PTPN11

Product Information

• Catalog No.: B0084-007855
• CAS No.: 1801747-42-1
• Molecular Formula: C16H19Cl2N5
• Molecular Weight: 352.26
• Storage: Store in a cool and dry place (or refer to the Certificate of Analysis).

Source

Original product source