CGI1746

Overview

CGI1746 is a small-molecule Btk inhibitor chemotype with a new binding mode that stabilizes an inactive nonphosphorylated enzyme conformation. CGI1746 has exquisite selectivity for Btk and inhibits both auto- and transphosphorylation steps necessary for enzyme activation.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Cancer | BTK

Product Information

• Catalog No.: B0084-430556
• CAS No.: 910232-84-7
• Molecular Formula: C34H37N5O4
• Molecular Weight: 579.69
• Purity: 98%

Source

Original product source