AT-406

Overview

AT-406 is a potent Smac mimetic and an antagonist of IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase), binding to XIAP-BIR3 (with Ki of 66.4 nM), cIAP1-BIR3(with Ki of 1.9 nM) and cIAP2-BIR3 (with Ki of 5.1 nM), respectively.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Cancer | IAP

Product Information

• Catalog No.: B0084-454116
• CAS No.: 1071992-99-8
• Molecular Formula: C32H43N5O4
• Molecular Weight: 561.71
• Purity: >98%

Source

Original product source