N-Arachidonyldopamine

Overview

N-Arachidonyldopamine acts as an Anandamide ( HY-10863 ) membrane transport inhibitor, a selective CB 1 cannabinoid receptor agonist, and a VR1 receptor activator. It exhibits an EC 50 value of 48 nM for rat VR1 and a K i value of 0.25 μM for CB1 . N-Arachidonyldopamine exists in mammalian neural tissues. It stimulates intracellular Ca 2+ mobilization, mediates cannabinoid-like effects, and induces hypothermia, hypomotility, catalepsy, analgesia, and hyperalgesia to heat. N-Arachidonyldopamine possesses anticancer activity against breast cancer . It can be used in research related to breast cancer and heat hyperalgesia.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Breast Cancer | Products > Disease Areas > Pain | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Cannabinoid Receptor | Products > Signaling Pathways > TRP Channel | Products > Signaling Pathways > Calcium Channel | Products > Signaling Pathways > Endogenous Metabolite

Product Information

• Catalog No.: HY-110018
• CAS No.: 199875-69-9
• Molecular Formula: C28H41NO3
• Molecular Weight: 439.63
• Purity: 98.36%
• Storage: Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (5.69 mM); Clear solution
• Availability: In-stock

Source

Original product source