THZ1

Overview

THZ1 is a selective CDK7 inhibitor that preferentially diminishes transcription in cancer cells. THZ1 has the unprecedented ability to target a remote cysteine residue located outside of the canonical kinase domain, providing an unanticipated means of achieving selectivity for CDK7. Cyclin-dependent kinases (CDKs) are involved in temporal control of the cell cycle and transcription and play central roles in cancer development and metastasis.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Cancer | CDK

Product Information

• Catalog No.: B0084-462601
• CAS No.: 1604810-83-4
• Molecular Formula: C31H28ClN7O2
• Molecular Weight: 566.062
• Purity: >98%

Source

Original product source