Polmacoxib

Overview

Polmacoxib is a first-in-class NSAID drug candidate that acts as a dual inhibitor of COX-2 and carbonic anhydrase (CA). It exhibits superior safety for cardiovascular, renal, and gastrointestinal tissues due to its dual COX-2 and CA binding properties. Polmacoxib inhibits premalignant and malignant colorectal lesions in mouse models, partly through inhibiting tumor cell proliferation. Source summary: Polmacoxib is a research-use small-molecule compound for biochemical studies, synthesis, and SAR research in inhibitor discovery workflows.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Cancer | Carbonic Anhydrase

Product Information

• Catalog No.: B0084-462767
• CAS No.: 301692-76-2
• Molecular Formula: C18H16FNO4S
• Molecular Weight: 361.387
• Purity: > 98%

Source

Original product source