AZD8186

Overview

AZD 8186 is a selective PI3Kβ/δ inhibitor (IC50= 0.003 μM for PI3Kβ, and 0.017 μM for PI3Kδ) with potential antineoplastic activity. It shows no significant binding against a panel of 442 other kinases when tested at a concentration of 10 µM and exhibits high oral efficacy in mouse cancer models.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Cancer | PI3K

Product Information

• Catalog No.: B0084-470885
• CAS No.: 1627494-13-6
• Molecular Formula: C24H25F2N3O4
• Molecular Weight: 457.4
• Storage: Store in a cool and dry place (or refer to the Certificate of Analysis).

Source

Original product source