GW843682X

Overview

GW843682X is a selective, ATP-competitive inhibitor of PLK1 and PLK3 , with IC 50 s of 2.2 nM and 9.1 nM, respectively, and is also >100-fold selective against ～30 other kinases.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Disease Areas > Blood Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Polo-like Kinase (PLK)

Product Information

• Catalog No.: HY-11003
• CAS No.: 660868-91-7
• Molecular Formula: C22H18F3N3O4S
• Molecular Weight: 477.46
• Purity: 99.89%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: 2.5 mg/mL (5.24 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source