JX 06

Overview

JX 06 is a potent, selective and covalent pyruvate dehydrogenase kinase (PDK) 1/2/3 inhibitor with IC50 values of 49, 101 and 313 nM for PDK1, PDK2 and PDK3, respectively. It suppresses A549 lung cancer cell proliferation in vitro and reduces tumor volume of A549 xenografts in mice.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Cancer | Pyruvate Dehydrogenase

Product Information

• Catalog No.: B2693-169680
• CAS No.: 729-46-4
• Molecular Formula: C10H16N2O2S4
• Molecular Weight: 324.51
• Purity: ≥98% by HPLC

Source

Original product source