SB525334

Overview

SB-525334 is a potent inhibitor of the TGF-β receptor 1 (TGF-β R1, ALK5) kinase (IC50 = 14.36 nM). It is ~4-fold less effective against ALK4 and inactive against ALK2, ALK3, and ALK6.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Cancer | TGF-β Receptor

Product Information

• Catalog No.: B2693-263896
• CAS No.: 356559-20-1
• Molecular Formula: C21H21N5
• Molecular Weight: 343.42494
• Purity: >98%

Source

Original product source