Alisertib

Overview

MLN8237 is a second-generation, orally bioavailable, highly selective small molecule inhibitor of the serine/threonine protein kinase Aurora A kinase with potential antineoplastic activity. Aurora kinase inhibitor MLN8237 binds to and inhibits Aurora A kinase, which may result in disruption of the assembly of the mitotic spindle apparatus, disruption of chromosome segregation, and inhibition of cell proliferation.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Cancer | Aurora Kinase

Product Information

• Catalog No.: B2693-336876
• CAS No.: 1028486-01-2
• Molecular Formula: C27H20ClFN4O4
• Molecular Weight: 518.9
• Purity: 0.98

Source

Original product source